Clinical Chemistry and Laboratory Medicine

Biography

Biography: Humphrey B.Osadolor

Abstract

Kutchalli drilling waste-pit materials in Nigerian National Petroleum Corporation (NNPC) exploration sites in Borno State was evaluated for systemic toxicity to inhabitants (man, animals and plants) via food chain. This is of particular interest because currently, waste pit manuals generated from exploration activities are not properly disposed of and therefore usually get washed away into various water bodies and arable farmlands through leaching sometimes. Plants and animals under these environmental conditions are used for food by man. In view of this fear, environmental impact assessment studies to ascertain the health risks to both plants (groundnut) and animals (New Zealand Rabbits) were carried out in this research study.The waste pit materials (soils) physico-chemical properties was determined. Phvtochemistry and seedling evaluation were assessed for the produce (groundnut) grown in the different kutchalli experimental waste pit material (KWPM). The produce in combination with guinea feed (growers' mash BFFM Ewu) were used to compound the feed regime and administered orally to New Zealand inbred rabbits. At the end of the analysis, the following results were obtained, the control (group 1) soil had plant height of 27 cm ± 0.2. leaf area 2.8cm² ± 0.3 while those grown in KWPM had plant height of 25cm ± 0.2, leaf area of 2.3cm² ± 0.1 and 23cm ± 0.3 and 1.6cm² ± 0.2 respectively. The relative dry matter yield for control plant was 9.7% while those of KWPM were 11.5% and 13.6% respectively. Heavy metals in the KWPM exceeded the rackground level by over 6times for Cd. 4 times for Cu, 3 times for Pb. 4 times for Mn (P <0.05). At the end of each specified period, the rabbits were sacrificed and the blood (plasma), liver, kidney, and heart were obtained for biochemical .and histopathological evaluation