Yogini Patel
Global Hospital & Research Centre, India
Title: Identifying the need of platelet transfusion for Dengue Epidemics in India
Biography
Biography: Yogini Patel
Abstract
Critical shortage of platelets in the city has lead to preferential transfusion of platelets. 600 patients were tested for NS1, screened for platelets count, mean platelet volume (MPV), IGG and IGM.
A significant difference in Chi Sq (p < 0.05) value was observed in patients with low platelet count, high MPV, not associated with overt bleeding as compared with patients with low platelet count, normal mean platelet volume and overt bleeding.
A regular follow up of platelet count test at six hourly interval revealed that the crisis period for an active dengue patient persists only for “twenty four hours”, and it can be easily overcome with simple intravenous (IV) saline transfusion for flushing and/or oral hydration.
Based on clinical diagnosis of overt bleeding, the decisions on platelet transfusion can be taken. As a result, we can avoid transfusion in around 60% of patients who are tested positive for NS1 dengue parameters and thereby overcoming the platelet shortage in management of dengue in India.