Clinical Chemistry in Oncology and Early Cancer Detection

Early detection and monitoring of cancer remain critical challenges in improving patient survival and treatment outcomes, and clinical chemistry plays an increasingly important role in addressing these challenges. This session focuses on the use of novel biomarkers, including protein markers, circulating tumor DNA (ctDNA), microRNAs, and metabolomic profiles, to detect cancer at its earliest stages and monitor treatment response. Advances in high-sensitivity assays, multiplex testing, and liquid biopsy technologies will be highlighted, demonstrating how clinical laboratories are moving toward less invasive, more accurate, and timely diagnostic solutions. The session will also explore the integration of molecular diagnostics, artificial intelligence, and bioinformatics in identifying predictive and prognostic markers, supporting personalized therapy decisions, and enhancing risk stratification. Challenges such as assay standardization, clinical validation, and implementation in routine practice will be discussed, along with translational research bridging laboratory discoveries with patient care. Participants will gain insights into how clinical chemistry is transforming oncology diagnostics, enabling early intervention, improved therapeutic monitoring, and better overall patient outcomes.

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